Do I need to cycle using Amino-XS®?
NO; Amino-XS® is a food supplement and does not contain any stimulants, therefore your body will not build up any "tolerance" to any of its ingredients. The human body has a constant need for proteins and amino acids and as such Amino-XS® can be used continually with out the need of any "off periods". Prolonged use of Amino-XS® will only lead to improved training, recovery and muscle gain.
What are essential amino acid's (EAA's)?
Essential amino acids or EAA's are amino acids that cannot be synthesised by the body and therefore have been dubbed as "essential" because these need to be consumed through the diet. There are 9 essential amino acids in total: phenylalanine, threonine,tryptophan, methionine, lysine, histidine, Valine, Isovaline & Leucine.
What are branched chain amino acids (BCAA's)?
Of course BCAA's are also essential amino acids, however, due to their unique molecular branch like structure, the three amino acids; Valine, Isovaline & Leucine, have been appropriately name as BCAA's or Branched Chain amino acids.
Is glutamine an essential amino acid?
Glutamine is most commonly reffered to as a non-essential amino acid. This is probably because it is the most abundant free amino acid in the human body. However new research indicates "that during catabolism, the tissue demands for glutamine exceed the endogenous production of this amino acid, resulting in a state of glutamine deficiency". Thus we feel that glutamine is more appropriately classed as conditionally essential..
What benefits does Glutamine have?
Aside from it's anti-catabolic properties, glutamine is also vital for proper immune function and studies show that immune cell replication requires glutamine. However, the conditionally essential glutamine cannot be synthesised by immune cells and therefore the "immune cost" of glutamine must be paid for by skeletal muscle cells. Needless to say this process leaves skeletal muscle tissue depeletd of glutamine and potentially in a catabolic state. This is one of the reasons we added a whopping 3 grams of glutamine per serving of Amino-XS.
Is taking large doses of glutamine on its own beneficial?
Needles to say that glutamine has a heap of benefits, but the answer is not so simple as to throw down a ton of powdered free-form l-glutamine to make up any deficit caused by intense training! Supplementing with large doses of pure glutamine leads to a significant increase in ammonia. This is bad news as ammonia is toxic to all cells, reduces glcogen synthesis, negatively affects kidney function, and amongst other things, is proven to decrease performance.
Therefore a succesful sports supplement should be able to provide a significant dose of glutamine, while being able to reduce ammonia accumulation. Amino-XS does just that by combining Alpha Ketoglutaric Acid (AKG) with high doses of branches chain amino acids (BCAA), glutamine and other essential amino acids (EAA's). AKG is the ammonia free carbon skeleton of glutamine and acts as an ammonia scavenger.
What is the significance of Alpha Ketoglutaric Acid in Amino-XS?
Because Alpha Ketoglutaric Acid has an ammonia free carbon chain, it has the ability to "mop up" excess ammonia and significantly reduce ammonia accumulation. AKG therefore works in perfect congruence with glutamine and the other BCAA's in maintaing an anti-catabolic/anabolic environment and supporting peak performance by reducing ammonia accumulation.
What do BCAA supplements do?
BCAA's have two main functions. The first is that they stimulate protein synthesis; Leucine is proven to trigger the mTOR pathway. In lay-terms, the triggering of mTOR sparks off the process of the construction of new muscle proteins. Providing all the other essential amino acids are present, new muscle tissue can be built - resulting in bigger muscles. BCAA's are highly anabolic. They second function of BCAA's is that they are anti-catabolic and therfore protect against muscle loss. BCAA's are the only amino acids that are burnt for energy directly in skeletal muscle tissue. Exercise, particularly resistance training induces the breakdown of muscle BCAA stores. Consuming BCAA's during training therefore also has an anti-catabolic effect.
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