-14%

Thermo XY Fat Burner for Men

Evidence-Based Fat Oxidation Support
Paradoxide® + EnXtra® & More
Energy For Hard Sessions
No Crash Formula
Sale price: £29.99 Regular price:£34.99

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Take one (1) serving of two (2) capsules daily with water. For optimum results take on an empty stomach. To assess tolerance initially consume one (1) capsule (1/2 a serving) per day.

Thermo-XY V 2.0:  An evidence-based fat burner that supports the breakdown of adipose tissue

Thermo-XY version 2.0 is a potent nutritional supplement specifically designed for men, supporting healthy and efficient fat loss as part of a balanced diet and lifestyle.

Who should use Thermo-XY?

Whether you're aiming to lose weight, burn stubborn belly fat, or hone your physique by dropping those last few pounds of excess fat, Thermo-XY is your go-to supplement.

This is because our advanced formula contains an array of ten scientifically backed ingredients, each one precisely dosed to deliver real results.

Together, these ingredients support the normal and efficient breakdown of stored body fat, and as a result support weight loss through multiple pathways.

For instance, naturally occurring compounds in Bitter Orange Peel, such as synephrine, help wiith the breakdown and mobilisation of free fatty acids from stored body at, supporting thermogenesis, and consequently aiding in fat oxidation.

ENXTRA® derived from Alpina galanga, plays a significant role not just in supporting healthy fat, but also aids in alertness, focus and energy levels making it Ideal for those low energy, low carb days. 

Additionally, Vitamin B1 (Thiamine), Vitamin B3 (Nicotinamide), and Vitamin B6 (Pyridoxine HCL) play crucial roles in energy metabolism, further aiding in fat metabolism.

With that said, we genuinely understand that targeting fat loss is absolutely no easy task, and while Thermo-XY can support you along your way in achieving your fat burning goals, it isn’t some other-worldly cure that instantly incinerates body fat.

Nor do we claim it to be the best fat burning pill in the world that will burn 7 pounds of fat in 1 week.

Nevertheless, we are certain that as with the thousands of people who are already enjoying the results, you will love it.

Harness the Power of Thermogenesis

Thermogenesis, the production of heat, is key to mobilising body fat. Thermo-XY's carefully dosed natural stimulants support this process, and our customers often report an increase in metabolic heat as they lose weight.

Transparency is one of our core values at DNA Lean®. We don’t make outlandish claims like “lose 20 lbs in one week” because that’s simply unrealistic.

For optimal weight loss, we recommend using Thermo-XY in conjunction with a healthy diet, regular exercise, and a balanced lifestyle.

This synergy between diet, exercise, and Thermo-XY creates a more effective fat-burning effect than any single factor alone.

Research-driven efficacious ingredients

We believe in full transparency. Our detailed breakdown of each ingredient explains its function and why it’s included, so you know exactly what you’re getting.

Unlike illegal fat burners, Thermo-XY contains natural ingredients compliant with UK laws and regulations, ensuring safety and efficacy. Always read the label and use as directed.

Experience the Thermo-XY difference today and take a decisive step towards achieving your weight loss goals.

Thiamin (Vitamin B1 as Thiamin Mononitrate), 30mg
Niacin (Vitamin B3 as Nicotinamide), 15mg
Vitamin B6 (as Pyridoxine HCL), 15mg
EnXtra® (Alpina galanga) (rhizome), 300mg
Bitter Orange (Citrus Aurantium whole fruit), 250mg
Vitacholine® (Choline bitartrate), 200mg
Caffeine Anhydrous, 100mg
Gotu Kola Extract (Equivalent to 500mg of herb), 50mg
Paradoxine® (Aframomum melegeuta) EXTRACT (Grains of Paradise), 40mg
Bioperine® (Piper nigrum) (FRUIT) EXTRACT, 5mg


Only intended for use by persons over the age of 18. Consult a medical practitioner prior to use if you have been treated for or diagnosed with or have a family history of any medical condition, or if you are using any prescription or over the counter drugs, including blood thinners. Discontinue use and consult a medical practitioner if unusual symptoms are experienced.

Thermo-XY® is best suited to men who want effective support during fat-loss phases, harder training blocks or periods where energy, focus and consistency matter most.

It may be ideal if you want a potent thermogenic formula that supports training intensity and daily output without relying on a messy, crash-heavy stimulant blend.

It is also a strong fit if you prefer a transparent formula built with evidence-based ingredients such as EnXtra®, Lean GBB, Paradoxine®, VitaCholine® and BioPerine®.

It is not designed to replace diet, training or discipline - it works best as part of a structured weight-management routine.

Order before 2pm on a working day and we’ll aim to dispatch your order the same day.

Enjoy free 48-hour shipping over £50 or free 24-hour shipping over £90.

Once your order is on its way, you’ll receive your delivery confirmation and shipping details via email, so your never left in the dark.

Every order is fully tracked and fully insured.

Thermo XY Fat Burner for Men
£29.99£34.99

Ingredients in-depth

Learn more about what’s in this product

Thiamin plays a crucial role in converting carbohydrates into energy, ensuring your body efficiently utilises stored fat as fuel. By supporting metabolic function and cellular energy production, this essential vitamin helps maintain steady energy levels, preventing fatigue while dieting. Research highlights its role in glucose metabolism, making it a key player in sustaining fat-burning processes during workouts.(Morris MS, et al. Am J Clin Nutr, 2012)

Niacin plays an important role for fat metabolism, aiding in the breakdown of fatty acids for energy. It supports optimal mitochondrial function, helping your body torch calories more efficiently. Additionally, niacin contributes to healthy blood circulation, ensuring nutrients reach your muscles faster for improved endurance and performance. Clinical studies confirm its role in lipid metabolism and thermogenesis.(Knip M, et al. Diabetologia, 2000)

Vitamin B6 is vital for fat and protein metabolism, ensuring your body efficiently converts stored fat into usable energy. It also helps regulate hormones, including those involved in stress and water retention—key concerns during fat loss. Research suggests B6 supports neurotransmitter function, helping to curb cravings and stabilise mood while dieting.(Dakshinamurti K, et al. J Nutr Sci Vitaminol, 1990)

EnXtra® is a natural energy enhancer that supports sustained alertness and fat metabolism without the crash. Research shows it amplifies thermogenesis and improves cognitive focus, making it a perfect addition to a stimulant-free fat burner. By increasing oxygen uptake and fat oxidation, it ensures your metabolism stays fired up.(Hengpratom T, et al. Phytomedicine, 2021)

Bitter Orange contains naturally occurring p-Synephrine, which is shown to activate beta-3 adrenergic receptors, which increase lipolysis and metabolic rate. This mechanism facilitates the breakdown of fat stores and enhances calorie burning, aiding in weight management and improved physical performance (Stohs et al., 2011).

VitaCholine®, a bioavailable form of choline, is crucial for fat metabolism as it supports the transport of fats and cholesterol. Choline aids in the production of acetylcholine, enhancing muscle function and endurance, which indirectly supports fat burning by improving workout efficiency and recovery (Zeisel & da Costa, 2009).

Caffeine Anhydrous stimulates the central nervous system, increasing energy levels and metabolic rate. It promotes the release of adrenaline, which triggers the breakdown of fatty acids from adipose tissue, making them available for energy use. This thermogenic effect enhances fat oxidation and boosts overall energy expenditure during exercise (Graham, 2001).

Gotu Kola Extract supports fat loss by improving circulation and reducing inflammation. Enhanced blood flow ensures efficient nutrient delivery to muscles, supporting recovery and growth. While not a direct fat burner, its benefits in reducing stress and promoting overall health complement a weight loss regimen by enhancing physical performance (Brinkhaus et al., 2000).

Paradoxine™, extracted from Grains of Paradise, enhances thermogenesis by increasing brown adipose tissue activity. This process boosts energy expenditure and calorie burning, promoting fat loss. Studies show that Paradoxine™ significantly increases metabolic rate, making it a valuable ingredient for supporting weight management (Sugita et al., 2013).

BioPerine® , derived from Piper nigrum, enhances the bioavailability of other nutrients, ensuring maximum absorption and efficacy. It stimulates thermogenesis, boosting metabolic rate and supporting fat burning. By improving nutrient uptake, BioPerine™ amplifies the fat-burning effects of other ingredients, aiding in weight loss and enhanced energy levels (Badmaev et al., 2000).

  • Combs, G. F. (2008). The Vitamins: Fundamental Aspects in Nutrition and Health. Academic Press.
  • Murray, M. T. (2000). Encyclopedia of Nutritional Supplements: The Essential Guide for Improving Your Health Naturally. Prima Publishing.
  • Leklem, J. E. (1990). Vitamin B-6: a status report. Journal of Nutrition, 120(11), 1503-1507.
  • Naghibi, F., Mosaddegh, M., Mohammadi Motamed, S., & Ghorbani, A. (2014). Labiatae family in folk medicine in Iran: from ethnobotany to pharmacology. Iranian Journal of Pharmaceutical Research, 4(2), 63-79.
  • Stohs, S. J., Preuss, H. G., & Shara, M. (2011). A review of the receptor-binding properties of p-synephrine as related to its pharmacological effects. Oxidative Medicine and Cellular Longevity, 2011.
  • Zeisel, S. H., & da Costa, K. A. (2009). Choline: an essential nutrient for public health. Nutrition Reviews, 67(11), 615-623.
  • Graham, T. E. (2001). Caffeine and exercise: metabolism, endurance and performance. Sports Medicine, 31(11), 785-807.
  • Brinkhaus, B., Lindner, M., Schuppan, D., & Hahn, E. G. (2000). Chemical, pharmacological and clinical profile of the East Asian medical plant Centella asiatica. Phytomedicine, 7(5), 427-448.
  • Sugita, J., Maruyama, K., Horii, Y., & Ishizuka, S. (2013). Enhancement of energy expenditure and fat oxidation by a combination of grains of paradise extract and caffeine in healthy humans: a randomized, double-blind, placebo-controlled, crossover study. Journal of Nutritional Science and Vitaminology, 59(4), 353-360.
  • Badmaev, V., Majeed, M., Norkus, E. P., & Prakash, S. (2000). Piperine, an alkaloid derived from black pepper, increases serum response of beta-carotene during 14-days of oral beta-carotene supplementation. Nutrition Research, 20(4), 451-456.
Built For The Cut DNA Lean Icon Energy With Intent DNA Lean Icon Train Harder. Stay Sharper DNA Lean Icon

Why Thermo-XY® is Different

Most men’s fat burners are built around one idea: overload them with stimulants and hope the customer mistakes feeling wired for real support.

Thermo-XY® takes a more complete approach. It combines a balanced stimulant profile with targeted ingredients such as EnXtra®, Lean GBB, Paradoxine®, VitaCholine® and BioPerine® to comprehensively support energy, focus, training intensity and fat-loss routines.

No random kitchen-sink blend. No pointless label dressing. No crash-heavy formula designed only to make you just “feel” something. Simply a transparent, performance-led thermogenic built for men who want sharper sessions and better results.

DNA Lean®

Why Thermo-XY® Stands Out

Thermo-XY® was built for men who want more from a fat burner - with targeted support for energy, focus and training intensity, without the messy, crash-heavy feel of typical stimulant formulas.
More Than Just Stimulants
Built with EnXtra®, Lean GBB, MitoBurn®, VitaCholine® and BioPerine® for a more complete thermogenic approach.
DNA Lean Thermo-XY fat burner for men angled product shot
Energy Without The Mess
Designed to support focus, output and training drive without relying on a harsh, overloaded formula that leaves you feeling burnt out.
Thermo-XY men’s thermogenic fat burner front label with formula details
Built For Harder Cutting Phases
A transparent formula created to support disciplined fat-loss routines, harder sessions and greater day-to-day consistency when results matter most.
Hand holding Thermo-XY capsules in front of DNA Lean men’s fat burner bottles

DNA Lean®

Frequently Asked Questions

They can help but work best when paired with a balanced diet and training. Thermo-XY is formulated to support energy, thermogenesis and body composition - not magically override poor habits. For example, Paradoxine® has strong human evidence for supporting visceral fat reduction.

No fat burner can “spot reduce” belly fat, but Thermo-XY can support the conditions that help reduce overall body fat: higher energy output, better training intensity and improved consistency.

The energy effect can be felt the same day, often within an hour, depending on your stimulation tolerance. Body composition changes usually need consistent use, diet and training over several weeks.

Thermo-XY is stimulant-led, so sensitive users may feel more alert. While this is perfectly normal, we suggest that you avoid taking it late in the evening, and monitor additional caffeine from coffee, pre-workout and energy drinks. EFSA states single caffeine doses up to 200mg are generally safe for healthy adults.

Usually, it’s better not to stack it with extra stimulants until you know your tolerance. If using coffee or pre-workout, keep total caffeine sensible and avoid combining multiple high-stim products.

  • 5 stars: 29 (97%)
  • 4 stars: 0 (0%)
  • 3 stars: 0 (0%)
  • 2 stars: 1 (3%)
  • 1 star: 0 (0%)
M
MD64
Nothing

Nothing. No change. Two a day early on empty stomach. 80kg 176cm and 21% body fat. Want to get to 16% body fat over few months through 3x CrossFit weekly some running plus 15% calorie deficit. Took these as stubborn body/plateau. These changed nothing no change at all in weight, fat or energy.

L
Luiza C.
Excellent

It s second time when i used it and it s a game changer,i lost 3 kg in 2 weeks

A
AJ
So far so good!

So far I’m super impressed. I’ve not even been on them a week however I’ve noticed a huge difference in how quickly my body fat is decreasing in only a few days and also targeting stubborn areas I struggled to shift previously. I’ve also not felt any side effects either that some fat burners I’ve tried before can usually provide. Definitely my “go to” for fat burners now

S
Shane

Found this great for energising me for the gym ,yeah great product

a
annette

Great product.

A
Andrew H.
Fat burners

Used them before great product used on empty stomach works wonders for me

P
Paul S.
EXCELLENT FAT BURNER

No comedown.

Make your cardio more focused and enjoyable :wink:

Hi Paul,

Thank youf ro taking the time out to leave your feedback, we genuinely appreciate this and are stoked that you love our products.

J
Jimii
Awesome for fat loss

I am currently following a strict diet and have been struggling to lose those last few pounds of stubborn belly fat. I have tried out grenade and a few other popular fat burners but none have really workled that well and allowed my to puch past this sticking point. These ones are great, I feel their effect within 15 minutes of taking them, I have lots of energy and sweat more and since using my first tub have last an extra 4 pounds pushing past my plateau.

Hello Jimii, thank you for taking the time out to leave us your feedback. We really appreciate this and are delighted to see you rated us 5 stars!

K
Kyle B.
Great for burning fat

Great product, take 2 on an empty stomach, 20 mins light cardio. Very effective 5* highly recommended

Hi Kyle, thank you for taking the time out to leave us your feedback. We really appreciate this and are delighted to see you rated us 5 stars!

D
Dean P.
Excellent

Another Excellent Product From Dna Lean..5 Stars..

Thank you for taking the time out to leave us your feedback Dean. We really appreciate this and are delighted to see you rated us 5 stars!

K
Kinga K.
Dna lean Thermo XY fat burner

The best fat burner i’ve ever tried.
Top quality :top::+1::skin-tone-4:

Z
Zubair
Superb, Highly Recommended!!!

I started taking these around 3 years ago and they are fantastic. They work instantly, you can literally see the difference within a week. My abs always start to show when I start taking these ahead of my training.

A
Ajmal'
Fantastic product

Started using the product around 12 weeks ago. In conjuction with a good diet and a training programme including some morning cardio, these helped hugely! I've always had lower excess fat which has been difficult to get rid of. This supplement has really targeted that area and now I'm as lean as ive ever been! On my 3rd bottle now!

N
Nathan W.
Great product

Great product improved energy levels

J
James
In my opinion the best fat burners on the market

I have used these fat burners for around 5 years now with consistent results over the time. Using these with a healthy diet (with treats when i feel like it) has helped me stay sub 10% bodyfat the whole time. Along side the fat burning effects, the general energy and mental focus these give is absolute amazing. Really helps with my manual work, the gym, looking after the kids and playing 5 a side with the lads. If your looking for a general boost in energy and something to help get that excess fat off then these are what you need.

P
Pamela R.
Great product

Always works for me

Z
Zubair
Superb, Highly Recommended!!!

I started taking these around 3 years ago and they are fantastic. They work instantly, you can literally see the difference within a week. My abs always start to show when I start taking these ahead of my training.

A
Ajmal'
Fantastic product

Started using the product around 12 weeks ago. In conjuction with a good diet and a training programme including some morning cardio, these helped hugely! I've always had lower excess fat which has been difficult to get rid of. This supplement has really targeted that area and now I'm as lean as ive ever been! On my 3rd bottle now!

N
Nathan W.
Great product

Great product improved energy levels

J
James
In my opinion the best fat burners on the market

I have used these fat burners for around 5 years now with consistent results over the time. Using these with a healthy diet (with treats when i feel like it) has helped me stay sub 10% bodyfat the whole time. Along side the fat burning effects, the general energy and mental focus these give is absolute amazing. Really helps with my manual work, the gym, looking after the kids and playing 5 a side with the lads. If your looking for a general boost in energy and something to help get that excess fat off then these are what you need.

P
Pamela R.
Great product

Always works for me

M
Matthew Reynolds
In my opinion the best fat burners on the market

I have used these fat burners for around 5 years now with consistent results over the time. Using these with a healthy diet (with treats when i feel like it) has helped me stay sub 10% bodyfat the whole time. Along side the fat burning effects, the general energy and mental focus these give is absolute amazing. Really helps with my manual work, the gym, looking after the kids and playing 5 a side with the lads. If your looking for a general boost in energy and something to help get that excess fat off then these are what you need.

N
Nathan Watts
Great product

Great product improved energy levels

A
Ajmal Shahzad
Fantastic product

Started using the product around 12 weeks ago. In conjuction with a good diet and a training programme including some morning cardio, these helped hugely! I've always had lower excess fat which has been difficult to get rid of. This supplement has really targeted that area and now I'm as lean as ive ever been! On my 3rd bottle now!

Z
Zubair Khan
Superb, Highly Recommended!!!

I started taking these around 3 years ago and they are fantastic. They work instantly, you can literally see the difference within a week. My abs always start to show when I start taking these ahead of my training.

P
Paul Cole
I love these fat burners!

I've been using the Therma XY for a while.

I started off on 1 tablet in a morning before eating and had great results. I moved up to 2 tablets and feel great.

Losing the lockdown excess weight was tough but was much easier with these.

D
D.
Dumping the excess fat cells ;-)

I've always had issues with removing the few excess pounds around midriff and I read about the positive results using this product and thought I would try if out.
Have to say in balance with my exercise regime they certainly did the job. I noticed immediate effects when taken on an empty stomach first thing upon waking.
Having reached my goal I continue to use this product to help maintain my weight to the level I'm at.. Great product and not too expensive so go ahead and try for yourself, you wont be disappointed ;-) Thanks DNA-Lean, two thumbs up

S
Steve Brown
The Best Fat Burner

I have used these fat burners previously when trying to lose then late few pounds and they are great!

P
Paul Sherriff
Its a must for fat loss

I was advised by Paul from DNA to take this supplement first thing upon waking. Do my cardio and fat literally melts off. Makes you in the mood for doing cardio if you wait 30 mins.Keeps you melting fat all day. Highly recommend these. Well done

J
Jeremy Young
It works

I've tried the fat burner to see whether it did something for me. Taking Paul from DNA Lean's advice on board, I took it at the right times and it helped me shift that last bit of fat. Really good, will buy more.